2023
Intestinal Knockout of Peroxisome Proliferator-activated Receptor-alpha Affects Structural Adaptation but not Liver Injury Following Massive Enterectomy
February 17, 2023
Phelps HM, Swanson KA, Steinberger AE, Guo J, King AC, Siddappa CM, Davidson NO, Rubin DC, Warner BW. Intestinal Knockout of Peroxisome Proliferator-activated Receptor-alpha Affects Structural Adaptation but not Liver Injury Following Massive Enterectomy. J Pediatr Surg. 2023 Feb 17:S0022-3468(23)00135-5. doi: 10.1016/j.jpedsurg.2023.02.016. Epub ahead of print. PMID: 36922278.
Disruption of Enterohepatic Circulation of Bile Acids Ameliorates Small Bowel Resection Associated Hepatic Injury
February 21, 2023
Tecos ME, Steinberger AE, Guo J, Rubin DC, Davidson NO, Warner BW. Disruption of Enterohepatic Circulation of Bile Acids Ameliorates Small Bowel Resection Associated Hepatic Injury. J Pediatr Surg. 2023 Feb 21:S0022-3468(23)00152-5. doi: 10.1016/j.jpedsurg.2023.02.031. Epub ahead of print. PMID: 36914459.
2022
Fecal microbiome and bile acid metabolome in adult short bowel syndrome
January 1, 2022
Boutte HJ Jr, Chen J, Wylie TN, Wylie KM, Xie Y, Geisman M, Prabu A, Gazit V, Tarr PI, Levin MS, Warner BW, Davidson NO, Rubin DC. Fecal microbiome and bile acid metabolome in adult short bowel syndrome. Am J Physiol Gastrointest Liver Physiol. 2022 Jan 1;322(1):G154-G168. doi: 10.1152/ajpgi.00091.2021. Epub 2021 Nov 24. PMID: 34816756; PMCID: PMC8793869.
SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
January 6, 2022
Gu W, Wang H, Huang X, Kraiczy J, Singh PNP, Ng C, Dagdeviren S, Houghton S, Pellon-Cardenas O, Lan Y, Nie Y, Zhang J, Banerjee KK, Onufer EJ, Warner BW, Spence J, Scherl E, Rafii S, Lee RT, Verzi MP, Redmond D, Longman R, Helin K, Shivdasani RA, Zhou Q. SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling. Cell Stem Cell. 2022 Jan 6;29(1):101-115.e10. doi: 10.1016/j.stem.2021.09.004. Epub 2021 Sep 27. PMID: 34582804; PMCID: PMC8741647.
Lipid absorption and overall intestinal lymphatic transport are impaired following partial small bowel resection in mice
July 7, 2022
Onufer EJ, Czepielewski RS, Han YH, Courtney CM, Sutton S, Sescleifer A, Randolph GJ, Warner BW. Lipid absorption and overall intestinal lymphatic transport are impaired following partial small bowel resection in mice. Sci Rep. 2022 Jul 7;12(1):11527. doi: 10.1038/s41598-022-15848-6. PMID: 35798817; PMCID: PMC9262882.
A novel maladaptive unfolded protein response as a mechanism for small bowel resection-induced liver injury
September 1, 2022
Steinberger AE, Tecos ME, Phelps HM, Rubin DC, Davidson NO, Guo J, Warner BW. A novel maladaptive unfolded protein response as a mechanism for small bowel resection-induced liver injury. Am J Physiol Gastrointest Liver Physiol. 2022 Sep 1;323(3):G165-G176. doi: 10.1152/ajpgi.00302.2021. Epub 2022 Jun 21. PMID: 35727920; PMCID: PMC9377788.
Distal Small Bowel Resection Yields Enhanced Intestinal and Colonic Adaptation
May 2022
Tecos ME, Steinberger AE, Guo J, Warner BW. Distal Small Bowel Resection Yields Enhanced Intestinal and Colonic Adaptation. J Surg Res. 2022 May;273:100-109. doi: 10.1016/j.jss.2021.11.015. Epub 2022 Jan 13. PMID: 35033819.
Being small for gestational age is not an independent risk factor for mortality in neonates with congenital diaphragmatic hernia: a multicenter study
September 2022
Zenilman A, Fan W, Hernan R, Wynn J, Abramov A, Farkouh-Karoleski C, Aspelund G, Krishnan US, Khlevner J, Azarow K, Crombleholme T, Cusick R, Chung D, Danko ME, Potoka D, Lim FY, McCulley DJ, Mychaliska GB, Schindel D, Soffer S, Wagner AJ, Warner BW, Chung WK, Duron VP. Being small for gestational age is not an independent risk factor for mortality in neonates with congenital diaphragmatic hernia: a multicenter study. J Perinatol. 2022 Sep;42(9):1183-1188. doi: 10.1038/s41372-022-01326-4. Epub 2022 Apr 21. PMID: 35449444.
2021
Risk factors for perioperative hypothermia and infectious outcomes in gastroschisis patients
July 2021
Bence CM, Landisch RM, Wu R, Szabo A, McElhinney K, Austin MT, Fraser JD, St Peter SD, Joshi S, Lillegard JB, Tay S, Warner BW, Kim AG, Perrone EE, Leys CM, Kohler JE, Wagner AJ. Risk factors for perioperative hypothermia and infectious outcomes in gastroschisis patients. J Pediatr Surg. 2021 Jul;56(7):1107-1112. doi: 10.1016/j.jpedsurg.2021.03.020. Epub 2021 Mar 26. PMID: 33865604.
Small Bowel Resection Increases Paracellular Gut Barrier Permeability via Alterations of Tight Junction Complexes Mediated by Intestinal TLR4
February 2021
Courtney CM, Onufer EJ, McDonald KG, Steinberger AE, Sescleifer AM, Seiler KM, Tecos ME, Newberry RD, Warner BW. Small Bowel Resection Increases Paracellular Gut Barrier Permeability via Alterations of Tight Junction Complexes Mediated by Intestinal TLR4. J Surg Res. 2021 Feb;258:73-81. doi: 10.1016/j.jss.2020.08.049. Epub 2020 Sep 28. PMID: 33002664; PMCID: PMC7937530.
Enterically derived high-density lipoprotein restrains liver injury through the portal vein
July 23, 2021
Han YH, Onufer EJ, Huang LH, Sprung RW, Davidson WS, Czepielewski RS, Wohltmann M, Sorci-Thomas MG, Warner BW, Randolph GJ. Enterically derived high-density lipoprotein restrains liver injury through the portal vein. Science. 2021 Jul 23;373(6553):eabe6729. doi: 10.1126/science.abe6729. PMID: 34437091; PMCID: PMC8478306.
Liver injury after small bowel resection is prevented in obesity-resistant 129S1/SvImJ mice
May 1, 2021
Onufer EJ, Han YH, Courtney C, Steinberger A, Tecos M, Sutton S, Sescleifer A, Ou J, Sanguinetti Czepielewski R, Randolph GJ, Warner BW. Liver injury after small bowel resection is prevented in obesity-resistant 129S1/SvImJ mice. Am J Physiol Gastrointest Liver Physiol. 2021 May 1;320(5):G907-G918. doi: 10.1152/ajpgi.00284.2020. Epub 2021 Mar 17. PMID: 33729834; PMCID: PMC8202193.
Rare and de novo variants in 827 congenital diaphragmatic hernia probands implicate LONP1 as candidate risk gene
October 7, 2021
Qiao L, Xu L, Yu L, Wynn J, Hernan R, Zhou X, Farkouh-Karoleski C, Krishnan US, Khlevner J, De A, Zygmunt A, Crombleholme T, Lim FY, Needelman H, Cusick RA, Mychaliska GB, Warner BW, Wagner AJ, Danko ME, Chung D, Potoka D, Kosiński P, McCulley DJ, Elfiky M, Azarow K, Fialkowski E, Schindel D, Soffer SZ, Lyon JB, Zalieckas JM, Vardarajan BN, Aspelund G, Duron VP, High FA, Sun X, Donahoe PK, Shen Y, Chung WK. Rare and de novo variants in 827 congenital diaphragmatic hernia probands implicate LONP1 as candidate risk gene. Am J Hum Genet. 2021 Oct 7;108(10):1964-1980. doi: 10.1016/j.ajhg.2021.08.011. Epub 2021 Sep 20. PMID: 34547244; PMCID: PMC8546037.
Antibiotic-driven intestinal dysbiosis in pediatric short bowel syndrome is associated with persistently altered microbiome functions and gut-derived bloodstream infections
January 2021
Thänert R, Thänert A, Ou J, Bajinting A, Burnham CD, Engelstad HJ, Tecos ME, Ndao IM, Hall-Moore C, Rouggly-Nickless C, Carl MA, Rubin DC, Davidson NO, Tarr PI, Warner BB, Dantas G, Warner BW. Antibiotic-driven intestinal dysbiosis in pediatric short bowel syndrome is associated with persistently altered microbiome functions and gut-derived bloodstream infections. Gut Microbes. 2021 Jan-Dec;13(1):1940792. doi: 10.1080/19490976.2021.1940792. PMID: 34264786; PMCID: PMC8284144.
2020
Comparative outcomes of right versus left congenital diaphragmatic hernia: A multicenter analysis
January 2020
Abramov A, Fan W, Hernan R, Zenilman AL, Wynn J, Aspelund G, Khlevner J, Krishnan U, Lim FY, Mychaliska GB, Warner BW, Cusick R, Crombleholme T, Chung D, Danko ME, Wagner AJ, Azarow K, Schindel D, Potoka D, Soffer S, Fisher J, McCulley D, Farkouh-Karoleski C, Chung WK, Duron V. Comparative outcomes of right versus left congenital diaphragmatic hernia: A multicenter analysis. J Pediatr Surg. 2020 Jan;55(1):33-38. doi: 10.1016/j.jpedsurg.2019.09.046. Epub 2019 Oct 26. PMID: 31677822.
Multicenter retrospective comparison of spontaneous intestinal perforation outcomes between primary peritoneal drain and primary laparotomy
July 2020
Ahle S, Badru F, Damle R, Osei H, Munoz-Abraham AS, Bajinting A, Barbian ME, Bhatia AM, Gingalewski C, Greenspon J, Hamilton N, Stitelman D, Strand M, Warner BW, Villalona GA. Multicenter retrospective comparison of spontaneous intestinal perforation outcomes between primary peritoneal drain and primary laparotomy. J Pediatr Surg. 2020 Jul;55(7):1270-1275. doi: 10.1016/j.jpedsurg.2019.07.007. Epub 2019 Jul 19. PMID: 31383579.
Increased Adiposity and Reduced Lean Body Mass in Patients with Short Bowel Syndrome
November 2020
Chiplunker AJ, Chen L, Levin MS, Warner BW, Davidson NO, Rubin DC. Increased Adiposity and Reduced Lean Body Mass in Patients with Short Bowel Syndrome. Dig Dis Sci. 2020 Nov;65(11):3271-3279. doi: 10.1007/s10620-019-06032-4. Epub 2020 Jan 7. PMID: 31907775; PMCID: PMC7924810.
Alterations in pancreatic islet cell function in response to small bowel resection
July 1, 2020
Courtney CM, Shyr ZA, Yan Z, Onufer EJ, Steinberger AE, Tecos ME, Barron LK, Guo J, Remedi MS, Warner BW. Alterations in pancreatic islet cell function in response to small bowel resection. Am J Physiol Gastrointest Liver Physiol. 2020 Jul 1;319(1):G36-G42. doi: 10.1152/ajpgi.00282.2019. Epub 2020 May 28. PMID: 32463335; PMCID: PMC7468758.
Changing the Paradigm for Management of Pediatric Primary Spontaneous Pneumothorax: A Simple Aspiration Test Predicts Need for Operation
January 2020
Leys CM, Hirschl RB, Kohler JE, Cherney-Stafford L, Marka N, Fallat ME, Gadepalli SK, Fraser JD, Grabowski J, Burns RC, Downard CD, Foley DS, Halleran DR, Helmrath MA, Kabre R, Knezevich MS, Lal DR, Landman MP, Lawrence AE, Mak GZ, Minneci PC, Musili N, Rymeski B, Saito JM, Sato TT, St Peter SD, Warner BW, Ostlie DJ; Midwest Pediatric Surgery Consortium MWPSC. Changing the Paradigm for Management of Pediatric Primary Spontaneous Pneumothorax: A Simple Aspiration Test Predicts Need for Operation. J Pediatr Surg. 2020 Jan;55(1):169-175. doi: 10.1016/j.jpedsurg.2019.09.043. Epub 2019 Oct 24. PMID: 31706614.
Extracorporeal Membrane Oxygenation for Pediatric Patients With Coronavirus Disease 2019-Related Illness
October 2020
MacGregor RM, Antiel RM, Najaf T, Said AS, Warner BW, Raval MV, Shakhsheer B. Extracorporeal Membrane Oxygenation for Pediatric Patients With Coronavirus Disease 2019-Related Illness. Pediatr Crit Care Med. 2020 Oct;21(10):893-897. doi: 10.1097/PCC.0000000000002432. PMID: 32427689; PMCID: PMC7523473.
EGFR in enterocytes & endothelium and HIF1α in enterocytes are dispensable for massive small bowel resection induced angiogenesis
September 15, 2020
Onufer EJ, Aladegbami B, Imai T, Seiler K, Bajinting A, Courtney C, Sutton S, Bustos A, Yao J, Yeh CH, Sescleifer A, Wang LV, Guo J, Warner BW. EGFR in enterocytes & endothelium and HIF1α in enterocytes are dispensable for massive small bowel resection induced angiogenesis. PLoS One. 2020 Sep 15;15(9):e0236964. doi: 10.1371/journal.pone.0236964. PMID: 32931498; PMCID: PMC7491746.
Effects of high-fat diet on liver injury after small bowel resection
June 2020
Onufer EJ, Han YH, Czepielewski RS, Courtney CM, Sutton S, Randolph GJ, Warner BW. Effects of high-fat diet on liver injury after small bowel resection. J Pediatr Surg. 2020 Jun;55(6):1099-1106. doi: 10.1016/j.jpedsurg.2020.02.037. Epub 2020 Feb 28. PMID: 32164985; PMCID: PMC7299751.
Nutrition in Necrotizing Enterocolitis and Following Intestinal Resection
February 18, 2020
Ou J, Courtney CM, Steinberger AE, Tecos ME, Warner BW. Nutrition in Necrotizing Enterocolitis and Following Intestinal Resection. Nutrients. 2020 Feb 18;12(2):520. doi: 10.3390/nu12020520. PMID: 32085587; PMCID: PMC7071274.
Likely damaging de novo variants in congenital diaphragmatic hernia patients are associated with worse clinical outcomes
December 2020
Qiao L, Wynn J, Yu L, Hernan R, Zhou X, Duron V, Aspelund G, Farkouh-Karoleski C, Zygumunt A, Krishnan US, Nees S, Khlevner J, Lim FY, Crombleholme T, Cusick R, Azarow K, Danko ME, Chung D, Warner BW, Mychaliska GB, Potoka D, Wagner AJ, Soffer S, Schindel D, McCulley DJ, Shen Y, Chung WK. Likely damaging de novo variants in congenital diaphragmatic hernia patients are associated with worse clinical outcomes. Genet Med. 2020 Dec;22(12):2020-2028. doi: 10.1038/s41436-020-0908-0. Epub 2020 Jul 28. PMID: 32719394; PMCID: PMC7710626.
Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model
March 2, 2020
Seiler KM, Bajinting A, Alvarado DM, Traore MA, Binkley MM, Goo WH, Lanik WE, Ou J, Ismail U, Iticovici M, King CR, VanDussen KL, Swietlicki EA, Gazit V, Guo J, Luke CJ, Stappenbeck T, Ciorba MA, George SC, Meacham JM, Rubin DC, Good M, Warner BW. Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model. Sci Rep. 2020 Mar 2;10(1):3842. doi: 10.1038/s41598-020-60672-5. PMID: 32123209; PMCID: PMC7051952.
Adaptation of extracellular matrix to massive small bowel resection in mice
June 2020
Seiler KM, Goo WH, Zhang Q, Courtney C, Bajinting A, Guo J, Warner BW. Adaptation of extracellular matrix to massive small bowel resection in mice. J Pediatr Surg. 2020 Jun;55(6):1107-1112. doi: 10.1016/j.jpedsurg.2020.02.038. Epub 2020 Feb 27. PMID: 32164986; PMCID: PMC7299777.
2019
Maintenance of piercing tracts in the perioperative period
May 2019
Drobish JK, Warner BW. Maintenance of piercing tracts in the perioperative period. J Clin Anesth. 2019 May;54:85-86. doi: 10.1016/j.jclinane.2018.10.021. Epub 2018 Nov 6. PMID: 30412816.
Lymphatic network remodeling after small bowel resection
June 2019
Onufer EJ, Czepielewski R, Seiler KM, Erlich E, Courtney CM, Bustos A, Randolph GJ, Warner BW. Lymphatic network remodeling after small bowel resection. J Pediatr Surg. 2019 Jun;54(6):1239-1244. doi: 10.1016/j.jpedsurg.2019.02.026. Epub 2019 Feb 28. PMID: 30879758; PMCID: PMC6545263.
Single-Cell Analysis Reveals Regional Reprogramming During Adaptation to Massive Small Bowel Resection in Mice
June 2019
Seiler KM, Waye SE, Kong W, Kamimoto K, Bajinting A, Goo WH, Onufer EJ, Courtney C, Guo J, Warner BW, Morris SA. Single-Cell Analysis Reveals Regional Reprogramming During Adaptation to Massive Small Bowel Resection in Mice. Cell Mol Gastroenterol Hepatol. 2019;8(3):407-426. doi: 10.1016/j.jcmgh.2019.06.001. Epub 2019 Jun 10. PMID: 31195149; PMCID: PMC6718927.
Short Bowel Syndrome
December 2019
Shakhsheer BA, Warner BW. Short Bowel Syndrome. Curr Treat Options Pediatr. 2019 Dec;5(4):494-505. doi: 10.1007/s40746-019-00179-y. Epub 2019 Oct 11. PMID: 33312846; PMCID: PMC7728382.
Impaired Chylomicron Assembly Modifies Hepatic Metabolism Through Bile Acid-Dependent and Transmissible Microbial Adaptations
October 2019
Xie Y, Matsumoto H, Kennedy S, Newberry EP, Moritz W, DeBosch BJ, Moley KH, Rubin DC, Warner BW, Kau AL, Tarr PI, Wylie TN, Wylie KM, Davidson NO. Impaired Chylomicron Assembly Modifies Hepatic Metabolism Through Bile Acid-Dependent and Transmissible Microbial Adaptations. Hepatology. 2019 Oct;70(4):1168-1184. doi: 10.1002/hep.30669. Epub 2019 May 23. PMID: 31004524; PMCID: PMC6783349.
Intestinal resection-associated metabolic syndrome
June 2018
Barron L, Courtney C, Bao J, Onufer E, Panni RZ, Aladegbami B, Warner BW. Intestinal resection-associated metabolic syndrome. J Pediatr Surg. 2018 Jun;53(6):1142-1147. doi: 10.1016/j.jpedsurg.2018.02.077. Epub 2018 Mar 7. PMID: 29588076; PMCID: PMC5994370.
An anatomic approach to understanding mechanisms of intestinal adaptation
August 2018
Courtney CM, Onufer EJ, Seiler KM, Warner BW. An anatomic approach to understanding mechanisms of intestinal adaptation. Semin Pediatr Surg. 2018 Aug;27(4):229-236. doi: 10.1053/j.sempedsurg.2018.07.002. Epub 2018 Jul 29. PMID: 30342597.
Remnant Small Bowel Length in Pediatric Short Bowel Syndrome and the Correlation with Intestinal Dysbiosis and Linear Growth
October 2018
Engelstad HJ, Barron L, Moen J, Wylie TN, Wylie K, Rubin DC, Davidson N, Cade WT, Warner BB, Warner BW. Remnant Small Bowel Length in Pediatric Short Bowel Syndrome and the Correlation with Intestinal Dysbiosis and Linear Growth. J Am Coll Surg. 2018 Oct;227(4):439-449. doi: 10.1016/j.jamcollsurg.2018.07.657. Epub 2018 Aug 2. PMID: 30077861; PMCID: PMC6162148.
Soybean-derived recombinant human epidermal growth factor protects against experimental necrotizing enterocolitis
June 2018
Isani M, Illingworth L, Herman E, Schmidt M, Barron L, Bowling J, Elizee M, Bai I, Gayer C, Grishin A, Erwin CR, Ford HR, Warner BW. Soybean-derived recombinant human epidermal growth factor protects against experimental necrotizing enterocolitis. J Pediatr Surg. 2018 Jun;53(6):1203-1207. doi: 10.1016/j.jpedsurg.2018.02.084. Epub 2018 Mar 8. PMID: 29636182.
Intestinal epithelial cell-specific Raptor is essential for high fat diet-induced weight gain in mice
November 10, 2018
Onufer EJ, Tay S, Barron LK, Courtney CM, Warner BW, Guo J. Intestinal epithelial cell-specific Raptor is essential for high fat diet-induced weight gain in mice. Biochem Biophys Res Commun. 2018 Nov 10;505(4):1174-1179. doi: 10.1016/j.bbrc.2018.10.040. Epub 2018 Oct 12. PMID: 30318117; PMCID: PMC6248877.
Epithelial cell specific Raptor is required for initiation of type 2 mucosal immunity in small intestine
July 17, 2017
Aladegbami B, Barron L, Bao J, Colasanti J, Erwin CR, Warner BW, Guo J. Epithelial cell specific Raptor is required for initiation of type 2 mucosal immunity in small intestine. Sci Rep. 2017 Jul 17;7(1):5580. doi: 10.1038/s41598-017-06070-w. PMID: 28717211; PMCID: PMC5514129.
Toll-like receptor 4 is critical for the development of resection-associated hepatic steatosis
June 2017
Barron LK, Bao JW, Aladegbami BG, Colasanti JJ, Guo J, Erwin CR, Warner BW. Toll-like receptor 4 is critical for the development of resection-associated hepatic steatosis. J Pediatr Surg. 2017 Jun;52(6):1014-1019. doi: 10.1016/j.jpedsurg.2017.03.026. Epub 2017 Mar 16. PMID: 28351520; PMCID: PMC5466889.
Epithelial IGF1R is dispensable for IGF2 mediated enhanced intestinal adaptation in retinoblastoma-deficient mice
June 2017
Sun RC, Choi PM, Diaz-Miron JL, Sommovilla J, Guo J, Erwin CR, Warner BW. Epithelial IGF1R is dispensable for IGF2 mediated enhanced intestinal adaptation in retinoblastoma-deficient mice. J Pediatr Surg. 2017 Jun;52(6):1026-1030. doi: 10.1016/j.jpedsurg.2017.03.030. Epub 2017 Mar 18. PMID: 28343662; PMCID: PMC5466888.
Intestinal Epithelial-Specific mTORC1 Activation Enhances Intestinal Adaptation After Small Bowel Resection
December 2016
Barron L, Sun RC, Aladegbami B, Erwin CR, Warner BW, Guo J. Intestinal Epithelial-Specific mTORC1 Activation Enhances Intestinal Adaptation After Small Bowel Resection. Cell Mol Gastroenterol Hepatol. 2016 Dec 10;3(2):231-244. doi: 10.1016/j.jcmgh.2016.10.006. PMID: 28275690; PMCID: PMC5331783.
Liver steatosis induced by small bowel resection is prevented by oral vancomycin
December 2016
Barron LK, Gayer CP, Roberts A, Golden JM, Aladegbami BG, Guo J, Erwin CR, Warner BW. Liver steatosis induced by small bowel resection is prevented by oral vancomycin. Surgery. 2016 Dec;160(6):1485-1495. doi: 10.1016/j.surg.2016.07.018. Epub 2016 Aug 31. PMID: 27592213; PMCID: PMC5409838.
Transgenic Soybean Production of Bioactive Human Epidermal Growth Factor (EGF)
June 17 2016
He Y, Schmidt MA, Erwin C, Guo J, Sun R, Pendarvis K, Warner BW, Herman EM. Transgenic Soybean Production of Bioactive Human Epidermal Growth Factor (EGF). PLoS One. 2016 Jun 17;11(6):e0157034. doi: 10.1371/journal.pone.0157034. PMID: 27314851; PMCID: PMC4912142.
The effect of impaired angiogenesis on intestinal function following massive small bowel resection
June 2015
Diaz-Miron J, Sun R, Choi P, Sommovilla J, Guo J, Erwin CR, Mei J, Scott Worthen G, Warner BW. The effect of impaired angiogenesis on intestinal function following massive small bowel resection. J Pediatr Surg. 2015 Jun;50(6):948-53. doi: 10.1016/j.jpedsurg.2015.03.014. Epub 2015 Mar 14. PMID: 25818317; PMCID: PMC4439276.
High-protein diet improves postoperative weight gain after massive small-bowel resection
March 2015
Sun RC, Choi PM, Diaz-Miron J, Sommovilla J, Guo J, Erwin CR, Warner BW. High-protein diet improves postoperative weight gain after massive small-bowel resection. J Gastrointest Surg. 2015 Mar;19(3):451-7. doi: 10.1007/s11605-014-2715-x. Epub 2014 Dec 18. PMID: 25519080; PMCID: PMC4965231.
Both epidermal growth factor and insulin-like growth factor receptors are dispensable for structural intestinal adaptation
June 2015
Sun RC, Diaz-Miron JL, Choi PM, Sommovilla J, Guo J, Erwin CR, Warner BW. Both epidermal growth factor and insulin-like growth factor receptors are dispensable for structural intestinal adaptation. J Pediatr Surg. 2015 Jun;50(6):943-7. doi: 10.1016/j.jpedsurg.2015.03.015. Epub 2015 Mar 14. PMID: 25818318; PMCID: PMC4439349.
Disruption of retinoblastoma protein expression in the intestinal epithelium impairs lipid absorption
May 15, 2014
Choi PM, Guo J, Erwin CR, Wandu WS, Leinicke JA, Xie Y, Davidson NO, Warner BW. Disruption of retinoblastoma protein expression in the intestinal epithelium impairs lipid absorption. Am J Physiol Gastrointest Liver Physiol. 2014 May 15;306(10):G909-15. doi: 10.1152/ajpgi.00067.2014. Epub 2014 Apr 17. PMID: 24742992; PMCID: PMC4024723.
High-fat diet enhances villus growth during the adaptation response to massive proximal small bowel resection
February 2014
Choi PM, Sun RC, Guo J, Erwin CR, Warner BW. High-fat diet enhances villus growth during the adaptation response to massive proximal small bowel resection. J Gastrointest Surg. 2014 Feb;18(2):286-94; discussion 294. doi: 10.1007/s11605-013-2338-7. Epub 2013 Sep 4. PMID: 24002772; PMCID: PMC4409787.
IGF-2 is necessary for retinoblastoma-mediated enhanced adaptation after small-bowel resection
November 2014
Choi PM, Sun RC, Sommovilla J, Diaz-Miron J, Guo J, Erwin CR, Warner BW. IGF-2 is necessary for retinoblastoma-mediated enhanced adaptation after small-bowel resection. J Gastrointest Surg. 2014 Nov;18(11):1887-93. doi: 10.1007/s11605-014-2586-1. Epub 2014 Jul 8. PMID: 25002022; PMCID: PMC4201888.
The role of enteral fat as a modulator of body composition after small bowel resection
August 2014
Choi PM, Sun RC, Sommovilla J, Diaz-Miron J, Khil J, Erwin CR, Guo J, Warner BW. The role of enteral fat as a modulator of body composition after small bowel resection. Surgery. 2014 Aug;156(2):412-8. doi: 10.1016/j.surg.2014.03.013. Epub 2014 Mar 14. PMID: 24713095; PMCID: PMC4099283.
CXCL5 is required for angiogenesis, but not structural adaptation after small bowel resection
June 2014
Rowland KJ, Diaz-Miron J, Guo J, Erwin CR, Mei J, Worthen GS, Warner BW. CXCL5 is required for angiogenesis, but not structural adaptation after small bowel resection. J Pediatr Surg. 2014 Jun;49(6):976-80; discussion 980. doi: 10.1016/j.jpedsurg.2014.01.034. Epub 2014 Feb 3. PMID: 24888846; PMCID: PMC4044536.
Insulin-like growth factor 2 and its enterocyte receptor are not required for adaptation in response to massive small bowel resection
Sun RC, Choi PM, Guo J, Erwin CR, Warner BW. Insulin-like growth factor 2 and its enterocyte receptor are not required for adaptation in response to massive small bowel resection. J Pediatr Surg. 2014 Jun;49(6):966-70; discussion 970. doi: 10.1016/j.jpedsurg.2014.01.035. Epub 2014 Jan 31. PMID: 24888844; PMCID: PMC4044537.
IGF-2 mediates intestinal mucosal hyperplasia in retinoblastoma protein (Rb)-deficient mice
June 2013
Choi P, Guo J, Erwin CR, Warner BW. IGF-2 mediates intestinal mucosal hyperplasia in retinoblastoma protein (Rb)-deficient mice. J Pediatr Surg. 2013 Jun;48(6):1340-7. doi: 10.1016/j.jpedsurg.2013.03.042. PMID: 23845628; PMCID: PMC3885982.
Up-regulation of hypoxia-inducible factor 1 alpha and hemodynamic responses following massive small bowel resection
June 2013
Rowland KJ, Yao J, Wang L, Erwin CR, Maslov KI, Wang LV, Warner BW. Up-regulation of hypoxia-inducible factor 1 alpha and hemodynamic responses following massive small bowel resection. J Pediatr Surg. 2013 Jun;48(6):1330-9. doi: 10.1016/j.jpedsurg.2013.03.031. PMID: 23845627; PMCID: PMC3755458.
Ret heterozygous mice have enhanced intestinal adaptation after massive small bowel resection
May 15, 2012
Hitch MC, Leinicke JA, Wakeman D, Guo J, Erwin CR, Rowland KJ, Merrick EC, Heuckeroth RO, Warner BW. Ret heterozygous mice have enhanced intestinal adaptation after massive small bowel resection. Am J Physiol Gastrointest Liver Physiol. 2012 May 15;302(10):G1143-50. doi: 10.1152/ajpgi.00296.2011. Epub 2012 Mar 15. PMID: 22421622; PMCID: PMC3362098.
Enterocyte expression of epidermal growth factor receptor is not required for intestinal adaptation in response to massive small bowel resection
September 2012
Rowland KJ, McMellen ME, Wakeman D, Wandu WS, Erwin CR, Warner BW. Enterocyte expression of epidermal growth factor receptor is not required for intestinal adaptation in response to massive small bowel resection. J Pediatr Surg. 2012 Sep;47(9):1748-53. doi: 10.1016/j.jpedsurg.2012.03.089. PMID: 22974617; PMCID: PMC3443391.
Immediate alterations in intestinal oxygen saturation and blood flow after massive small bowel resection as measured by photoacoustic microscopy
June 2012
Rowland KJ, Yao J, Wang L, Erwin CR, Maslov KI, Wang LV, Warner BW. Immediate alterations in intestinal oxygen saturation and blood flow after massive small bowel resection as measured by photoacoustic microscopy. J Pediatr Surg. 2012 Jun;47(6):1143-9. doi: 10.1016/j.jpedsurg.2012.03.020. PMID: 22703784; PMCID: PMC3377986.
p38 MAPK regulates Bax activity and apoptosis in enterocytes at baseline and after intestinal resection
May 1, 2012
Wakeman D, Guo J, Santos JA, Wandu WS, Schneider JE, McMellen ME, Leinicke JA, Erwin CR, Warner BW. p38 MAPK regulates Bax activity and apoptosis in enterocytes at baseline and after intestinal resection. Am J Physiol Gastrointest Liver Physiol. 2012 May 1;302(9):G997-1005. doi: 10.1152/ajpgi.00485.2011. Epub 2012 Mar 1. PMID: 22383494; PMCID: PMC3362074.
Deletion of p38-alpha mitogen-activated protein kinase within the intestinal epithelium promotes colon tumorigenesis
August 2012
Wakeman D, Schneider JE, Liu J, Wandu WS, Erwin CR, Guo J, Stappenbeck TS, Warner BW. Deletion of p38-alpha mitogen-activated protein kinase within the intestinal epithelium promotes colon tumorigenesis. Surgery. 2012 Aug;152(2):286-93. doi: 10.1016/j.surg.2012.05.009. PMID: 22828150; PMCID: PMC3408636.
Bacterial DNA content in the intestinal wall from infants with necrotizing enterocolitis
June 2011
Bucher BT, McDuffie LA, Shaikh N, Tarr PI, Warner BB, Hamvas A, White FV, Erwin CR, Warner BW. Bacterial DNA content in the intestinal wall from infants with necrotizing enterocolitis. J Pediatr Surg. 2011 Jun;46(6):1029-33. doi: 10.1016/j.jpedsurg.2011.03.026. PMID: 21683193; PMCID: PMC3118995.
Intestinal adaptation after small bowel resection in human infants
June 2011
McDuffie LA, Bucher BT, Erwin CR, Wakeman D, White FV, Warner BW. Intestinal adaptation after small bowel resection in human infants. J Pediatr Surg. 2011 Jun;46(6):1045-51. doi: 10.1016/j.jpedsurg.2011.03.027. PMID: 21683196; PMCID: PMC3121576.
Epidermal growth factor receptor signaling modulates chemokine (CXC) ligand 5 expression and is associated with villus angiogenesis after small bowel resection
August 2010
McMellen ME, Wakeman D, Erwin CR, Guo J, Warner BW. Epidermal growth factor receptor signaling modulates chemokine (CXC) ligand 5 expression and is associated with villus angiogenesis after small bowel resection. Surgery. 2010 Aug;148(2):364-70. doi: 10.1016/j.surg.2010.03.020. Epub 2010 May 14. PMID: 20471049; PMCID: PMC2917230.
Extent of small bowel resection does not influence the magnitude of intestinal adaptation in the mouse
June 2010
Wakeman D, Longshore SW, McMellen ME, Santos JA, Guo J, Erwin CR, Warner BW. Extent of small bowel resection does not influence the magnitude of intestinal adaptation in the mouse. J Pediatr Surg. 2010 Jun;45(6):1274-9. doi: 10.1016/j.jpedsurg.2010.02.101. PMID: 20620331; PMCID: PMC3112353.
Retinoblastoma protein (pRb), but not p107 or p130, is required for maintenance of enterocyte quiescence and differentiation in small intestine
January 2, 2009
Guo J, Longshore S, Nair R, Warner BW. Retinoblastoma protein (pRb), but not p107 or p130, is required for maintenance of enterocyte quiescence and differentiation in small intestine. J Biol Chem. 2009 Jan 2;284(1):134-140. doi: 10.1074/jbc.M806133200. Epub 2008 Nov 3. PMID: 18981186; PMCID: PMC2610504.
p21(waf1/cip1) deficiency does not perturb the intestinal crypt stem cell population after massive small bowel resection
June 2009
Longshore SW, Nair R, Perrone EE, Erwin CR, Guo J, Warner BW. p21(waf1/cip1) deficiency does not perturb the intestinal crypt stem cell population after massive small bowel resection. J Pediatr Surg. 2009 Jun;44(6):1065-71; discussion 1071. doi: 10.1016/j.jpedsurg.2009.02.034. PMID: 19524718; PMCID: PMC2697119.
Intestinal resection induces angiogenesis within adapting intestinal villi
June 2009
Martin CA, Perrone EE, Longshore SW, Toste P, Bitter K, Nair R, Guo J, Erwin CR, Warner BW. Intestinal resection induces angiogenesis within adapting intestinal villi. J Pediatr Surg. 2009 Jun;44(6):1077-82; discussion 1083. doi: 10.1016/j.jpedsurg.2009.02.036. PMID: 19524720; PMCID: PMC2697129.
Resection-induced intestinal adaptation and the role of enteric smooth muscle
June 2008
Martin CA, Bernabe KQ, Taylor JA, Nair R, Paul RJ, Guo J, Erwin CR, Warner BW. Resection-induced intestinal adaptation and the role of enteric smooth muscle. J Pediatr Surg. 2008 Jun;43(6):1011-7. doi: 10.1016/j.jpedsurg.2008.02.015. PMID: 18558175.
Body composition and metabolic changes associated with massive intestinal resection in mice
January 2008
Tantemsapya N, Meinzner-Derr J, Erwin CR, Warner BW. Body composition and metabolic changes associated with massive intestinal resection in mice. J Pediatr Surg. 2008 Jan;43(1):14-9. doi: 10.1016/j.jpedsurg.2007.09.010. PMID: 18206448.
Lessons learned: optimization of a murine small bowel resection model
June 2008
Taylor JA, Martin CA, Nair R, Guo J, Erwin CR, Warner BW. Lessons learned: optimization of a murine small bowel resection model. J Pediatr Surg. 2008 Jun;43(6):1018-24. doi: 10.1016/j.jpedsurg.2008.02.025. PMID: 18558176; PMCID: PMC2481288.